Target cells are sensitized for cytotoxic T-lymphocyte-mediated destruction by estradiol and tamoxifen.

Volume: 58, Issue: 1, Pages: 64 - 68
Published: Jul 1, 1994
Abstract
The effect of estradiol (E2) and tamoxifen (TX) on cytotoxic T-tymphocyte (CTL)-mediated target-cell lysis was studied. CTL was generated in mixed cultures of rat spleen cells, using female Fischer 344 rat cells as responders and female Wistar rat cells or Nb2 rat lymphoma cells as stimulators. Concanavalin-A-stimulated Wistar lymphoblasts or Nb2 cells were used as targets. CTL harvested on day 5 exerted 16-25% cytotoxicity when used at...
Paper Details
Title
Target cells are sensitized for cytotoxic T-lymphocyte-mediated destruction by estradiol and tamoxifen.
Published Date
Jul 1, 1994
Volume
58
Issue
1
Pages
64 - 68
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