Data quality control in genetic case-control association studies
Abstract
This protocol details the steps for data quality assessment and control that are typically carried out during case-control association studies. The steps described involve the identification and removal of DNA samples and markers that introduce bias. These critical steps are paramount to the success of a case-control study and are necessary before statistically testing for association. We describe how to use PLINK, a tool for handling SNP data,...
Paper Details
Title
Data quality control in genetic case-control association studies
Published Date
Aug 26, 2010
Journal
Volume
5
Issue
9
Pages
1564 - 1573
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