Membrane crystallization of lysozyme under forced solution flow

The production of protein crystals with adequate size and high lattice perfection for X-ray analysis appears as the bottleneck for obtaining diffraction data at a resolution sufficient to establish 3D structure-function correlation. In previous investigations, microporous hydrophobic membranes have emerged as effective tools for macromolecular crystallization: polymeric supports have been used both to generate a controlled supersaturated...