Oxidative Alterations in Alzheimer's Disease
Abstract
There is increasing evidence that free radical damage to brain lipids, carbohydrates, proteins, and DNA is involved in neuron death in neurodegenerative disorders. The largest number of studies have been performed in Alzheimer's disease (AD) where there is considerable support for the oxidative stress hypothesis in the pathogenesis of neuron degeneration. In autopsied brain there is an increase in lipid peroxidation, a decline in polyunsaturated...
Paper Details
Title
Oxidative Alterations in Alzheimer's Disease
Published Date
Jan 1, 1999
Journal
Volume
9
Issue
1
Pages
133 - 146
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