Dopamine-dependent motor learning: Insight into L-dopa's long-duration response
Abstract
Dopamine (DA) is critical for motor performance, motor learning, and corticostriatal plasticity. The relationship between motor performance and learning, and the role of DA in the mediation of them, however, remain unclear.To examine this question, we took advantage of PITx3-deficient mice (aphakia mice), in which DA in the dorsal striatum is reduced by 90%. PITx3-deficient mice do not display obvious motor deficits in their home cage, but are...
Paper Details
Title
Dopamine-dependent motor learning: Insight into L-dopa's long-duration response
Published Date
Jan 1, 2009
Journal
Pages
NA - NA
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