Pancreatic secretion, hepatic extraction, and plasma clearance of insulin from steady-state insulin and C-peptide measurements in critically ill patients
Abstract
null null Hyperglycaemia is prevalent in critical illness and clinical practice is to reduce blood glucose by intravenous insulin infusion. We estimated pancreatic secretion, hepatic first-pass extraction ratio and plasma insulin clearance per minute from measured serum C-peptide and insulin in 9 critically ill adults in a pseudo steady-state situation, i.e. when nutrition and insulin infusion remained at a constant rate up to the test (min 20,...
Paper Details
Title
Pancreatic secretion, hepatic extraction, and plasma clearance of insulin from steady-state insulin and C-peptide measurements in critically ill patients
Published Date
Jan 1, 2014
Journal
Volume
47
Issue
3
Pages
10964 - 10969
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