Pancreatic secretion, hepatic extraction, and plasma clearance of insulin from steady-state insulin and C-peptide measurements in critically ill patients

Volume: 47, Issue: 3, Pages: 10964 - 10969
Published: Jan 1, 2014
Abstract
null null Hyperglycaemia is prevalent in critical illness and clinical practice is to reduce blood glucose by intravenous insulin infusion. We estimated pancreatic secretion, hepatic first-pass extraction ratio and plasma insulin clearance per minute from measured serum C-peptide and insulin in 9 critically ill adults in a pseudo steady-state situation, i.e. when nutrition and insulin infusion remained at a constant rate up to the test (min 20,...
Paper Details
Title
Pancreatic secretion, hepatic extraction, and plasma clearance of insulin from steady-state insulin and C-peptide measurements in critically ill patients
Published Date
Jan 1, 2014
Volume
47
Issue
3
Pages
10964 - 10969
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