Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis

Volume: 92, Pages: 274 - 298
Published: Oct 1, 2013
Abstract
Organisms are constantly challenged by stressors and thus the maintenance of biomolecules functionality is essential for the assurance of cellular homeostasis. Proteins carry out the vast majority of cellular functions by mostly participating in multimeric protein assemblies that operate as protein machines. Cells have evolved a complex proteome quality control network for the rescue, when possible, or the degradation of damaged polypeptides....
Paper Details
Title
Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis
Published Date
Oct 1, 2013
Volume
92
Pages
274 - 298
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