Tetramethylpyrazine suppresses interleukin-8 expression in LPS-stimulated human umbilical vein endothelial cell by blocking ERK, p38 and nulear factor-κB signaling pathways

Volume: 125, Issue: 1, Pages: 83 - 89
Published: Aug 17, 2009
Abstract
null null Aim of the study null To determine the anti-inflammatory effects of Tetramethylpyrazine (TMP) and to investigate the inhibitory effect of TMP on IL-8 production in human umbilical vein endothelial cells (HUVECs) induced by LPS might be mediated by inhibiting p38, ERK and NF-κB signaling pathways. null null null Materials and methods null HUVECs were treated with or without TMP for 24 h before exposure to LPS for 4 h. IL-8 gene and...
Paper Details
Title
Tetramethylpyrazine suppresses interleukin-8 expression in LPS-stimulated human umbilical vein endothelial cell by blocking ERK, p38 and nulear factor-κB signaling pathways
Published Date
Aug 17, 2009
Volume
125
Issue
1
Pages
83 - 89
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