Original paper
Identification of seven loci affecting mean telomere length and their association with disease
Abstract
Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer and several age-associated diseases. We report here a genome-wide meta-analysis of 37,684 individuals with replication of selected variants in an additional 10,739 individuals. We identified seven loci, including five new loci, associated with mean LTL (P < 5 × 10(-8)). Five of the loci contain candidate genes (TERC, TERT, NAF1, OBFC1 and RTEL1) that are...
Paper Details
Title
Identification of seven loci affecting mean telomere length and their association with disease
Published Date
Mar 27, 2013
Journal
Volume
45
Issue
4
Pages
422 - 427
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Notes
History