Development of an alternative approach to protein crystallization

Volume: 8, Issue: 4, Pages: 193 - 198
Published: Nov 24, 2007
Abstract
We are developing an alternate strategy for the crystallization of macromolecules that does not, like current methods, depend on the optimization of traditional variables such as pH and precipitant concentration, but is based on the hypothesis that many conventional small molecules might establish stabilizing, intermolecular, non covalent crosslinks in crystals, and thereby promote lattice formation. To test the hypothesis, we carried out...
Paper Details
Title
Development of an alternative approach to protein crystallization
Published Date
Nov 24, 2007
Volume
8
Issue
4
Pages
193 - 198
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