Polymorphisms of the CYP1B1 gene may be associated with the onset of natural menopause in Chinese women
Abstract
The Cytochrome P450 1B1 (CYP1B1) is one of the major CYP450 enzymes catalyzing 4-hydroxylation, an important elimination step for estrogens. Relatively little is known, however, about the impact of this gene on the onset and cessation of menstruation, which are the significant milestones in a woman's life and predictors of many hormone related diseases. In this report, we described the association of four SNPs in the CYP1B1 gene, Arg48Gly,...
Paper Details
Title
Polymorphisms of the CYP1B1 gene may be associated with the onset of natural menopause in Chinese women
Published Date
Oct 1, 2006
Journal
Volume
55
Issue
3
Pages
238 - 246
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