Association of μ-opioid receptor gene (OPRM1) haplotypes with postoperative nausea and vomiting
Abstract
Genetic variants, such as single-nucleotide polymorphisms (SNPs), of the μ-opioid receptor gene (OPRM1) might be associated with individual differences in opioid sensitivity, as well as with the incidence and severity of postoperative nausea and vomiting (PONV). The goal of the present study was to determine, in a cohort of Japanese surgical patients, genotypes and haplotypes of several SNPs in the OPRM1 gene, and their association with PONV...
Paper Details
Title
Association of μ-opioid receptor gene (OPRM1) haplotypes with postoperative nausea and vomiting
Published Date
May 24, 2014
Journal
Volume
232
Issue
8
Pages
2627 - 2635
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History