Molecular Interactions between NAFLD and Xenobiotic Metabolism
Abstract
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, is a complex multifactorial disease characterized by metabolic deregulations that include accumulation of lipids in the liver, lipotoxicity, and insulin resistance. The progression of NAFLD to non-alcoholic steatohepatitis and cirrhosis, and ultimately to carcinomas, is governed by interplay of pro-inflammatory pathways, oxidative stress, as well as...
Paper Details
Title
Molecular Interactions between NAFLD and Xenobiotic Metabolism
Published Date
Jan 1, 2013
Journal
Volume
4
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Notes
History