Molecular Mechanisms of Autophagy in the Cardiovascular System
Abstract
Autophagy is a catabolic recycling pathway triggered by various intra- or extracellular stimuli that is conserved from yeast to mammals. During autophagy, diverse cytosolic constituents are enveloped by double-membrane vesicles, autophagosomes, which later fuse with lysosomes or the vacuole to degrade their cargo. Dysregulation in autophagy is associated with a diverse range of pathologies including cardiovascular disease, the leading cause of...
Paper Details
Title
Molecular Mechanisms of Autophagy in the Cardiovascular System
Published Date
Jan 30, 2015
Journal
Volume
116
Issue
3
Pages
456 - 467
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