Interaction of Glycyrrhizin and Glycyrrhetinic Acid with DNA

Volume: 31, Issue: 1, Pages: 114 - 121
Published: Jan 1, 2012
Abstract
Glycyrrhizin (GL), a molecule of glycyrrhetinic acid (GA), is an aqueous extract from licorice root. These compounds are well known for their anti-inflammatory, hepatocarcinogenesis, antiviral, and interferon-inducing activities. This study is the first attempt to investigate the binding of GL and GA with DNA. The effect of ligand complexation on DNA aggregation and condensation was investigated in aqueous solution at physiological conditions,...
Paper Details
Title
Interaction of Glycyrrhizin and Glycyrrhetinic Acid with DNA
Published Date
Jan 1, 2012
Volume
31
Issue
1
Pages
114 - 121
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