Ultrasensitivity part III: cascades, bistable switches, and oscillators

•The previous installments in this series reviewed several mechanisms for generating ultrasensitivity. •In this review, we examine how ultrasensitivity can contribute to the functioning of more complex systems. •Ultrasensitivity can allow cascades to transmit signals effectively. •Ultrasensitivity is important for the generation of bistability by positive feedback loops. •Ultrasensitivity promotes the generation of limit cycle oscillations by...