Preparation of amoxicillin intragastric buoyant sustained-release tablets and the dissolution characteristics
Abstract
An intragastric buoyant sustained-release tablet (IGB-T) containing 100 mg of amoxicillin (AMX) was prepared to eradicate gastric Helicobacter pylori. A tablet prepared by compressing the mixture of hydroxypropylcellulose-H (HPC-H), citric acid (17.2 mg), sodium hydrogen carbonate (22.8 mg) and AMX was employed as the basic system for preparing IGB-T. The weight and diameter of the tablets were designed to be about 300 mg and 10 mm,...
Paper Details
Title
Preparation of amoxicillin intragastric buoyant sustained-release tablets and the dissolution characteristics
Published Date
Feb 1, 2006
Volume
110
Issue
3
Pages
581 - 586
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