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Role of Deep Abdominal Fat in the Association Between Regional Adipose Tissue Distribution and Glucose Tolerance in Obese Women
Published on Mar 1, 1989in Diabetes 7.27
· DOI :10.2337/diab.38.3.304
Jean-Pierre Després109
Estimated H-index: 109
André Nadeau51
Estimated H-index: 51
+ 6 AuthorsClaude Bouchard128
Estimated H-index: 128
Computed tomography (CT) was used to study the association between adipose tissue localization and glucose tolerance in a sample of 52 premenopausal obese women aged 35.7 ± 5.5 yr (mean ± SD) and with a body fat of 45.9 ± 5.5%. Body-fat mass and the body mass index (BMI) were significantly correlated with plasma glucose, insulin, and connecting peptide (C-peptide) areas after glucose (75 g) ingestion (.40 ≥ r ≤ .51, P r = .76, P r = .59, P r = .29, P r = .44 and .49, respectively; P r = .57, P
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Cited By381
Published on Jan 1, 2014
Rebecca E. Hasson11
Estimated H-index: 11
(University of Michigan),
Michael I. Goran84
Estimated H-index: 84
(University of Southern California)
Ethnic differences in the incidence and prevalence of certain obesity-related cancers are well established. African Americans have increased risk of prostate, breast (premenopausal), and colorectal cancer and myeloma, compared to Caucasians with the lowest rates in Latinos, Asians, and Native Americans. Prior work in this area suggests that there are distinct ethnic differences in obesity-related metabolic risk factors for cancer, insulin resistance in particular, that are evident early in life,...
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Published on Dec 10, 2012
Russell R. Pate89
Estimated H-index: 89
Maria Oria8
Estimated H-index: 8
+ 1 AuthorsNutrition Board12
Estimated H-index: 12
55 Citations Source Cite
Published on Dec 1, 2001in Atherosclerosis 4.47
Jean Bergeron49
Estimated H-index: 49
(Laval University),
Charles Couillard35
Estimated H-index: 35
(Laval University)
+ 6 AuthorsClaude Bouchard128
Estimated H-index: 128
(Louisiana State University)
Endurance exercise training is known to produce favorable changes in the metabolic profile including reduced plasma triglyceride (TG) and increased high-density lipoprotein (HDL) cholesterol concentrations. These metabolic improvements are likely to contribute to the reduced coronary heart disease (CHD) risk often observed in physically active individuals. However, the physiological mechanisms responsible for such improvements in TG and HDL cholesterol concentrations with endurance exercise are ...
35 Citations Source Cite
Published on Jan 1, 1997
James O. Hill1
Estimated H-index: 1
Obesity, a risk factor for noninsulin-dependent diabetes mellitus (NIDDM), cardiovascular disease (CVD), and some types of cancer (1), is increasing in the US population at an alarming rate. The recent National Health and Nutrition Examination Survey III (NHANES III), taken from 1988–1991, shows that the prevalence of obesity among US adults is currently about 33% (2). This compares to 25% seen in the previous NHANES II survey, taken from 1976–1980. This survey shows that children as well as adu...
3 Citations Source Cite
Published on Jul 1, 2008in Sleep 5.13
Katherine A. Stamatakis20
Estimated H-index: 20
(Johns Hopkins University),
Mark H. Sanders44
Estimated H-index: 44
(University of Pittsburgh)
+ 4 AuthorsNaresh M. Punjabi49
Estimated H-index: 49
(Johns Hopkins University)
SLEEP DISORDERED BREATHING (SDB) IS A PREVALENT AND CHRONIC CONDITION THAT IS CHARACTERIZED BY RECURRENT EPISODES OF UPPER AIRWAY collapse during sleep. It is estimated that approximately 7% of adults in the general population have SDB of at least moderate severity.1 Several epidemiological and clinic-based studies have shown that the prevalence of altered glucose metabolism and type 2 diabetes increases with severity and frequency of self-reported and objective measures of SDB, independent of a...
49 Citations
Published on Jan 1, 2007
Robert J. Kuczmarski1
Estimated H-index: 1
4 Citations Source Cite
Published on Jan 1, 1999
Jean-Pierre Després109
Estimated H-index: 109
André Marette53
Estimated H-index: 53
It is commonly accepted that obesity is a health hazard associated with complications such as non-insulin-dependent diabetes mellitus (Type 2 diabetes), dyslipidemias, hypertension and cardiovascular diseases (1–5). On the basis of its increasing prevalence in affluent countries (6–8), obesity is considered as a major cause of morbidity and mortality which makes a major contribution to our health care expenditures (9). Overall, excess weight is related to an increased mortality rate both from ca...
12 Citations Source Cite
Published on Mar 1, 2000in Medical Clinics of North America 2.58
Michael T. Sheehan8
Estimated H-index: 8
(Mayo Clinic),
Michael Dennis Jensen69
Estimated H-index: 69
Obesity has long been recognized as contributing to a variety of adverse health consequences. Despite the growing body of evidence of these risks, the prevalence of obesity continues to increase in North America (see the article by Allison elsewhere in this issue). Obesity is associated with insulin resistance with or without type II diabetes mellitus (DM), hypertension, dyslipidemia, and cardiovascular disease. This clustering of metabolic abnormalities has been referred to as syndrome X , 104 ...
52 Citations Source Cite
View next paperDistribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden.