Mass spectrometry-based proteomics: from cancer biology to protein biomarkers, drug targets, and clinical applications.

Volume: 2014, Issue: 34, Pages: 504 - 510
Published: May 15, 2014
Abstract
Proteomics is optimally suited to bridge the gap between genomic information on the one hand and biologic functions and disease phenotypes at the other, since it studies the expression and/or post-translational modification (especially phosphorylation) of proteins--the major cellular players bringing about cellular functions--at a global level in biologic specimens. Mass spectrometry technology and (bio)informatic tools have matured to the...
Paper Details
Title
Mass spectrometry-based proteomics: from cancer biology to protein biomarkers, drug targets, and clinical applications.
Published Date
May 15, 2014
Volume
2014
Issue
34
Pages
504 - 510
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