Change of Conformation of DNA by Association with Proteins

A comparison of the conformation in solution of DNA‐protein associations with that of free DNA has been carried out for lysozyme, ribonuclease and bovine serum albumin. The solutions have been studied simultaneously by ultracentrifugation, light‐scattering, spectropolarimetry and viscometry. From the data it can be concluded: For DNA‐ribonuclease and DNA‐bovine serum albumin complexes, the interaction forces between complex particles themselves...