Insulin Resistance and the Cardiometabolic Syndrome in HIV Infection

Highly active antiretroviral therapy (HAART) has dramatically improved the prognosis of HIV‐positive patients. However, long‐term adverse effects of this therapy include dyslipidemia, insulin resistance (IR), changes in body fat distribution (lipodystrophy), and cardiometabolic syndrome (CMS). IR in HIV‐positive patients does not seem to represent a significant independent risk factor for the development of cardiovascular disease; nevertheless,...