Benzo(a)pyrene promotes A549 cell migration and invasion through up-regulating Twist

Volume: 89, Issue: 3, Pages: 451 - 458
Published: May 22, 2014
Abstract
Benzo(a)pyrene (BaP) is one of the strongest carcinogens in cigarette smoke, which is an established human carcinogen. Twist, a transcription factor of the basic helix–loop–helix class, is reported to regulate lung cancer metastasis. Evidence has shown that BaP could induce Twist mRNA expression in non-small cell lung cancer (NSCLC) cell line A549 and promote lung adenocarcinoma cell invasion. However, it is unclear whether BaP promotes the...
Paper Details
Title
Benzo(a)pyrene promotes A549 cell migration and invasion through up-regulating Twist
Published Date
May 22, 2014
Volume
89
Issue
3
Pages
451 - 458
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