Original paper
Chloroquine-N-oxide, a major oxidative degradation product of chloroquine: Identification, synthesis and characterization
Volume: 81-82, Pages: 118 - 125
Published: Jul 1, 2013
Abstract
Chloroquine (CQ) (1) which has endured as one of the most powerful antimalarial drugs was subjected to oxidative stress conditions and the degradation profile was studied. The oxidative stress condition of CQ furnished one major degradation product along with other minor degradation products. The unknown major degradation product was identified in HPLC and pure impurity was isolated using column chromatography. The structure of this major...
Paper Details
Title
Chloroquine-N-oxide, a major oxidative degradation product of chloroquine: Identification, synthesis and characterization
Published Date
Jul 1, 2013
Volume
81-82
Pages
118 - 125
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Notes
History