CXCL5 abundant in the wound fluid at the late phase of wound healing, possibly promoting migration of mesenchymal stem cells and vascular tube formation

We previously reported that wound fluid generated from injured cornea at 5 day after injury had ability to induce mesenchymal to epithelial transition (MET) of circulating mesenchymal stem cells (MSCs). In the present study, we further analyzed wound fluid by cytokine array. Comparing with normal cornea, increased expression of chemokines CXCL2, CXCL3, CXCL5, CCL2, anti-inflammatory cytokine IL-10, growth factors VEGF and β-NGF, protease...