Neutrophil extracellular traps in patients with sepsis

Volume: 194, Issue: 1, Pages: 248 - 254
Published: Mar 1, 2015
Abstract
Release of neutrophil extracellular traps (NETs) has been identified as an important aspect of innate immunity. We examined whether sepsis had any influence on ex vivo generation of NETs by neutrophils.We isolated neutrophils from consecutive patients with sepsis (n = 17) and without sepsis (n = 18) admitted to the intensive care unit. Neutrophils were activated by incubation with phorbol-12-myristate-13-acetate (PMA) to induce release of NETs,...
Paper Details
Title
Neutrophil extracellular traps in patients with sepsis
Published Date
Mar 1, 2015
Volume
194
Issue
1
Pages
248 - 254
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