Pathophysiology of arrhythmogenic cardiomyopathy
Abstract
Arrhythmogenic cardiomyopathy (AC) is a clinically and genetically heterogeneous disorder of heart muscle that is associated with ventricular arrhythmias and risk of sudden cardiac death, particularly in the young and athletes. Mutations in five genes that encode major components of the desmosomes, namely junction plakoglobin, desmoplakin, plakophilin-2, desmoglein-2, and desmocollin-2, have been identified in approximately half of affected...
Paper Details
Title
Pathophysiology of arrhythmogenic cardiomyopathy
Published Date
Nov 29, 2011
Journal
Volume
9
Issue
4
Pages
223 - 233
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