Development of immunosensors for direct detection of three wound infection biomarkers at point of care using electrochemical impedance spectroscopy.
Abstract
A method for label-free, electrochemical impedance immunosensing for the detection and quantification of three infection biomarkers in both buffer and directly in the defined model matrix of mock wound fluid is demonstrated. Triggering Receptor-1 Expressed on Myeloid cells (TREM-1) and Matrix MetalloPeptidase 9 (MMP-9) are detected via direct assay and N-3-oxo-dodecanoyl-l-HomoSerineLactone (HSL), relevant in bacterial quorum sensing, is...
Paper Details
Title
Development of immunosensors for direct detection of three wound infection biomarkers at point of care using electrochemical impedance spectroscopy.
Published Date
Jan 15, 2012
Volume
31
Issue
1
Pages
413 - 418
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