Bioinformatic and immunological analysis reveals lack of support for measles virus related mimicry in Crohn’s disease

Volume: 12, Issue: 1
Published: Aug 28, 2014
Abstract
A link between measles virus and Crohn’s disease (CD) has been postulated. We assessed through bioinformatic and immunological approaches whether measles is implicated in CD induction, through molecular mimicry. The BLAST2p program was used to identify amino acid sequence similarities between five measles virus and 56 intestinal proteins. Antibody responses to measles/human mimics were tested by an in-house ELISA using serum samples from 50...
Paper Details
Title
Bioinformatic and immunological analysis reveals lack of support for measles virus related mimicry in Crohn’s disease
Published Date
Aug 28, 2014
Volume
12
Issue
1
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