Regulation of antiviral T cell responses by type I interferons
Abstract
Type I interferons (IFNs) are pro-inflammatory cytokines that are rapidly induced in different cell types during viral infections. The consequences of type I IFN signalling include direct antiviral activity, innate immune cell activation and regulation of adaptive immune responses. In this Review, we discuss recent conceptual advances in our understanding of indirect and direct regulation of T cell immunity by type I IFNs, which can either...
Paper Details
Title
Regulation of antiviral T cell responses by type I interferons
Published Date
Mar 20, 2015
Journal
Volume
15
Issue
4
Pages
231 - 242
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History