Ethanol shock and lysozyme aggregation
Abstract
Irreversible protein–protein aggregation is associated with several human maladies, including Alzheimer's disease, and poses a challenge to pharmaceutical formulation and preservation efforts. The existence of multiple agglomeration pathways that lead to different final morphologies complicates the ability to determine the aggregation fate of proteins under various reaction conditions. Using lysozyme (3 mg mL−1) as a model protein for dynamic...
Paper Details
Title
Ethanol shock and lysozyme aggregation
Published Date
Jan 1, 2013
Journal
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Notes
History