28 Long-term Administration of 5-Hydroxytryptophan in Down's Syndrome
Abstract
Patients with trisomy-21 Down's syndrome have been demonstrated to have a depression of whole blood 5-hydroxytryptamine (serotonin) (5HT). In older mongol children 5HT levels are usually around 50 % of normal while in the newborn a wide variation of levels from normal to as low as 10 % can be demonstrated. Fourteen hypotonic babies with trisomy-21 have been given 5-hydroxytryptophan (5HTP) in an attempt to raise the whole blood 5HT. Oral 5HTP...
Paper Details
Title
28 Long-term Administration of 5-Hydroxytryptophan in Down's Syndrome
Published Date
May 1, 1967
Journal
Volume
1
Issue
3
Pages
207 - 207
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