Pharmacological Characterization of Cultivated Neuronal Networks: Relevance to Synaptogenesis and Synaptic Connectivity

Volume: 34, Issue: 5, Pages: 757 - 776
Published: Apr 19, 2014
Abstract
Mental disorders, such as schizophrenia or Alzheimer's disease, are associated with impaired synaptogenesis and/or synaptic communication. During development, neurons assemble into neuronal networks, the primary supracellular mediators of information processing. In addition to the orchestrated activation of genetic programs, spontaneous electrical activity and associated calcium signaling have been shown to be critically involved in the...
Paper Details
Title
Pharmacological Characterization of Cultivated Neuronal Networks: Relevance to Synaptogenesis and Synaptic Connectivity
Published Date
Apr 19, 2014
Volume
34
Issue
5
Pages
757 - 776
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