Inclusive composite interval mapping (ICIM) for digenic epistasis of quantitative traits in biparental populations
Abstract
It has long been recognized that epistasis or interactions between non-allelic genes plays an important role in the genetic control and evolution of quantitative traits. However, the detection of epistasis and estimation of epistatic effects are difficult due to the complexity of epistatic patterns, insufficient sample size of mapping populations and lack of efficient statistical methods. Under the assumption of additivity of QTL effects on the...
Paper Details
Title
Inclusive composite interval mapping (ICIM) for digenic epistasis of quantitative traits in biparental populations
Published Date
Jan 1, 2008
Volume
116
Issue
2
Pages
243 - 260
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