High quality drug screening by capillary electrophoresis: A review

Volume: 773, Pages: 24 - 36
Published: Apr 1, 2013
Abstract
High quality assays are needed in drug discovery to reduce the high attrition rate of lead compounds during primary screening. Capillary electrophoresis (CE) represents a versatile micro-separation technique for resolution of enzyme-catalyzed reactions, including substrate(s), product(s), cofactor(s) and their stereoisomers, which is needed for reliable characterization of biomolecular interactions in free solution. This review article provides...
Paper Details
Title
High quality drug screening by capillary electrophoresis: A review
Published Date
Apr 1, 2013
Volume
773
Pages
24 - 36
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