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Common marmoset as a new model animal for neuroscience research and genome editing technology

Published on Jan 1, 2014in Development Growth & Differentiation1.64
· DOI :10.1111/dgd.12109
Noriyuki Kishi11
Estimated H-index: 11
(Keio: Keio University),
Kenya Sato3
Estimated H-index: 3
(Central Institute for Experimental Animals)
+ 1 AuthorsHideyuki Okano110
Estimated H-index: 110
(Keio: Keio University)
Abstract
The common marmoset (Callithrix jacchus) is a small New World primate; it originally comes from the Atlantic coastal forests in northeastern Brazil. It has been attracting much attention in the biomedical research field because of its size, availability, and unique biological characteristics. Its endocrinological and behavioral similarity to humans, comparative ease in handling, and high reproductive efficiency are very advantageous for neuroscience research. Recently, we developed transgenic common marmosets with germline transmission, and this technological breakthrough provides a potential paradigm shift by enabling researchers to investigate complex biological phenomena using genetically-modified non-human primates. In this review, we summarize recent progress in marmoset research, and also discuss a potential application of genome editing tools that should be useful toward the generation of knock-out/knock-in marmoset models.
  • References (80)
  • Citations (90)
References80
Newest
#1Hui Yang (MIT: Massachusetts Institute of Technology)H-Index: 16
#2Haoyi Wang (MIT: Massachusetts Institute of Technology)H-Index: 24
Last.Rudolf Jaenisch (MIT: Massachusetts Institute of Technology)H-Index: 173
view all 6 authors...
#1Thomas Gaj (Scripps Research Institute)H-Index: 22
#2Charles A. Gersbach (Duke University)H-Index: 38
Last.Carlos F. Barbas (Scripps Research Institute)H-Index: 96
view all 3 authors...
#1Ken-ichi T. Suzuki (Hiroshima University)H-Index: 15
#2Yukiko Isoyama (Hiroshima University)H-Index: 1
Last.Takashi Yamamoto (Hiroshima University)H-Index: 43
view all 9 authors...
#1Haoyi Wang (MIT: Massachusetts Institute of Technology)H-Index: 24
#2Hui Yang (MIT: Massachusetts Institute of Technology)H-Index: 16
Last.Rudolf Jaenisch (MIT: Massachusetts Institute of Technology)H-Index: 173
view all 7 authors...
#1Le Cong (MIT: Massachusetts Institute of Technology)H-Index: 15
#2F. Ann Ran (MIT: Massachusetts Institute of Technology)H-Index: 9
Last.Luciano A. Marraffini (Rockefeller University)H-Index: 33
view all 11 authors...
#1Prashant Mali (Harvard University)H-Index: 29
#2Luhan Yang (Harvard University)H-Index: 15
Last.George M Church G M (Wyss Institute for Biologically Inspired Engineering)H-Index: 135
view all 8 authors...
#1Keigo Hikishima (Central Institute for Experimental Animals)H-Index: 14
#2Kazuhiko Sawada (Tsukuba International University)H-Index: 10
Last.Atsushi Iriki (Riken-BSI: RIKEN Brain Science Institute)H-Index: 36
view all 13 authors...
#1Young Hoon Sung (Yonsei University)H-Index: 10
#2In Jeoung Baek (UOU: University of Ulsan)H-Index: 2
Last.H.W. LeeH-Index: 30
view all 9 authors...
Cited By90
Newest
#1Sho Yoshimatsu (Keio: Keio University)H-Index: 1
#2Junko Okahara (Central Institute for Experimental Animals)H-Index: 5
Last.Hideyuki Okano (Keio: Keio University)H-Index: 110
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#1Wakako Kumita (Central Institute for Experimental Animals)H-Index: 2
#2Kenya Sato (Central Institute for Experimental Animals)H-Index: 3
Last.Yasubumi Sakakibara (Keio: Keio University)H-Index: 29
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#1F.A. Ermatinger (UZH: University of Zurich)
#2R.K. Brügger (UZH: University of Zurich)
Last.Judith M. Burkart (UZH: University of Zurich)H-Index: 23
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#1Ehsan Sedaghat-Nejad (Johns Hopkins University)H-Index: 3
#2David J. Herzfeld (Johns Hopkins University)H-Index: 6
Last.Reza Shadmehr (Johns Hopkins University)H-Index: 60
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#1Samuel U. Nummela (UCSD: University of California, San Diego)H-Index: 6
#2Michael J. Jutras (UW: University of Washington)H-Index: 2
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