Rescuing US biomedical research from its systemic flaws

Published on Apr 22, 2014in Proceedings of the National Academy of Sciences of the United States of America9.58
· DOI :10.1073/pnas.1404402111
Bruce M. Albertsll72
Estimated H-index: 72
(UCSF: University of California, San Francisco),
Marc W. Kirschner149
Estimated H-index: 149
(Harvard University)
+ 1 AuthorsHarold E. Varmus120
Estimated H-index: 120
The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession—and making it difficult for seasoned investigators to produce their best work. This is a recipe for long-term decline, and the problems cannot be solved with simplistic approaches. Instead, it is time to confront the dangers at hand and rethink some fundamental features of the US biomedical research ecosystem.
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