Molecular docking and inhibition studies of α-amylase activity by labdane diterpenes from Alpinia nigra seeds

Volume: 23, Issue: 11, Pages: 4836 - 4852
Published: Jun 10, 2014
Abstract
Wide varieties of synthetic drugs are available for combating type 2 diabetes but are not free of associated side effects. Commercially available antidiabetic drugs are known to be potent inhibitors of α-amylase which reduce postprandial hyperglycaemia. Here, we have investigated Alpinia nigra seed extracts and the isolated two labdane diterpenes (I and II) for the α-amylase inhibitory activity. These labdane type diterpenes showed more...
Paper Details
Title
Molecular docking and inhibition studies of α-amylase activity by labdane diterpenes from Alpinia nigra seeds
Published Date
Jun 10, 2014
Volume
23
Issue
11
Pages
4836 - 4852
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