Differences in the effects of solution additives on heat- and refolding-induced aggregation.
Abstract
Although a number of low-molecular-weight additives have been developed to suppress protein aggregation, it is unclear whether these aggregation suppressors affect various aggregation processes in the same manner. In this study, we evaluated the differences in the effect of solution additives on heat- and refolding-induced aggregation in the presence of guanidine (Gdn), arginine (Arg), and spermidine (Spd), and the comparable analysis showed the...
Paper Details
Title
Differences in the effects of solution additives on heat- and refolding-induced aggregation.
Published Date
Mar 1, 2008
Journal
Volume
24
Issue
2
Pages
436 - 443
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Notes
History