Diverse CRISPRs evolving in human microbiomes
Abstract
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci, together with cas (CRISPR–associated) genes, form the CRISPR/Cas adaptive immune system, a primary defense strategy that eubacteria and archaea mobilize against foreign nucleic acids, including phages and conjugative plasmids. Short spacer sequences separated by the repeats are derived from foreign DNA and direct interference to future infections. The availability of...
Paper Details
Title
Diverse CRISPRs evolving in human microbiomes
Published Date
Jun 13, 2012
Journal
Volume
8
Issue
6
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