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Rheumatic heart disease in developing countries.

Published on Aug 2, 2007in The New England Journal of Medicine70.67
· DOI :10.1056/NEJMp078039
Jonathan R. Carapetis63
Estimated H-index: 63
Abstract
Rheumatic fever has receded as an important health problem in wealthy countries. Dr. Jonathan Carapetis writes that for everyone else, rheumatic fever and rheumatic heart disease are bigger problems than ever and warrant urgent attention.
  • References (5)
  • Citations (177)
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References5
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#1Eloi MarijonH-Index: 39
#2Phalla OuH-Index: 21
Last. Xavier JouvenH-Index: 55
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#1Jonathan R. Carapetis (Royal Children's Hospital)H-Index: 63
#2Andrew C Steer (Royal Children's Hospital)H-Index: 43
Last. Martin WeberH-Index: 32
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#1Malcolm I. McDonald (CDU: Charles Darwin University)H-Index: 19
#2Bart J. Currie (CDU: Charles Darwin University)H-Index: 74
Last. Jonathan R. Carapetis (Royal Children's Hospital)H-Index: 63
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Summary Acute rheumatic fever (ARF) remains a major problem in tropical regions, resource-poor countries, and minority indigenous communities. It has long been thought that group A streptococcal (GAS) pharyngitis alone was responsible for acute rheumatic fever; this belief has been supported by laboratory and epidemiological evidence gathered over more than 60 years, mainly in temperate climates where GAS skin infection is uncommon. GAS strains have been characterised as either rheumatogenic or ...
174 CitationsSource
THE prevention of recurrences of rheumatic fever depend on the protection of the patient against infection with Group A streptococci. The daily oral administration of sulfonamides or penicillin has been employed with considerable success for this purpose.1 The major limitation of continuous oral chemoprophylaxis is that patients are apt to forget to take their medication regularly. For this reason the administration of penicillin parenterally by infrequent injections may afford a more reliable m...
68 CitationsSource
#1Floyd W. DennyH-Index: 1
#2Lewis W. WannamakerH-Index: 31
Last. Edward CusterH-Index: 4
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The prevention of acute rheumatic fever by the prompt treatment of streptococcic infections with penicillin has been attempted in this study. The results obtained show that this attempt was successful, and, because of their importance, these results are presented here in a preliminary report. The significance of an adequate means of prevention may be realized when it is considered that rheumatic fever develops in an estimated 200,000 to 250,000 persons in the general population of the United Sta...
272 CitationsSource
Cited By177
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#1Kaciane K.B. Oliveira (UFMG: Universidade Federal de Minas Gerais)H-Index: 4
#2Bruno Ramos Nascimento (Faculdade de Medicina da Universidade Federal de Minas Gerais)H-Index: 15
Last. Waydder Antônio A. Costa (Faculdade de Medicina da Universidade Federal de Minas Gerais)
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Rheumatic Heart Disease Educational Strategies Introduction: The burden of rheumatic heart disease (RHD) is still high in Brazil. Lack of population awareness about the disease limits the efficacy of prevention programs. We aimed to evaluate the effectiveness of education on RHD in schools, comparing the conventional expository teaching method with tablet-based worked examples. Method: A prospective, cluster randomized trial was conducted over eight months in six randomly selected low-income Bra...
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#1Yusra Ribhi Shawar (Johns Hopkins University)H-Index: 2
#2Jeremy Shiffman (Johns Hopkins University)H-Index: 2
Background Rheumatic heart disease (RHD) poses a high burden in low-income countries, as well as among indigenous and other socioeconomically disadvantaged populations in high-income countries. Despite its severity and preventability, RHD receives insufficient global attention and resources. We conducted a qualitative policy analysis to investigate the reasons for recent growth but ongoing inadequacy in global priority for addressing RHD. Methods and Results Drawing on social science scholarship...
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#1Rachel C Heenan (Royal Children's Hospital)H-Index: 2
#2Tom Parks (University of Oxford)H-Index: 11
Last. Andrew C Steer (Royal Children's Hospital)H-Index: 43
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BACKGROUND: Rheumatic heart disease (RHD) is a chronic valvular heart disease that is responsible for a heavy burden of premature mortality in low- and middle-income countries. The total costs of RHD are important to health policy and research investment decisions. We estimate for the first time the total cost of RHD for Fiji (2008-2012) using a cost-of-illness approach and novel primary data on RHD disease burden and costs. METHODS: RHD cases were identified using probabilistic record linkage a...
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Abstract Problem considered Acute rheumatic fever (ARF) is a major problem of public health in developing countries like Morocco. This study was done to find out the clinical manifestations and laboratory features of patients with ARF in Fez city. Methods A retrospective study was conducted from 2009 to 2015 in the pediatric ward of the university hospital Hassan II of Fez. A total of 209 children ( Results The mean age of ARF cases were 11 years. The sex ratio male/female was 0.9. The most repr...
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Valve heart diseases are one of the cornerstones of cardiovascular medicine, being these diseases accountable for significant morbidity and mortality with a high prevalence. The main objective of this book is to approach this group of diseases from a holistic point of view, reviewing all the aspects of the several entities and summarizing all the available evidence together with the guidelines from the main scientific societies in this field, in order to help in the study and the decision-making...
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#1Semra Atalay (Ankara University)H-Index: 18
#1Semra AtalayH-Index: 2
Last. Melih Timucin Dogan (Ankara University)H-Index: 1
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BACKGROUND: The aim of this study is to investigate the prevalence of subclinical rheumatic heart disease in schoolchildren aged 5-18 by using portable echocardiography in Ankara, Turkey. METHODS: The portable echocardiography screening was performed by a paediatric cardiologist for all of the cases. The mean age of 2550 healthy students was 11.09 ± 2.91 years (1339 females, 1211 males) in three private and three public schools. Echocardiographic studies were assessed according to 2012 World Hea...
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#1D.P. Morberg (University of California, Berkeley)H-Index: 1
#2Y.A. Alzate López (UFBA: Federal University of Bahia)H-Index: 1
Last. M.S. Burroughs Peña (Stanford University)H-Index: 1
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Abstract Objectives Rheumatic heart disease (RHD) is a preventable disease frequently recognized in urban slums. Disease rates in Brazilian slums are incommensurate with the country's economic status and the existence of its universal healthcare system. Our study aimed to investigate what system issues may allow for disease persistence, focusing on issues surrounding access and utilization of primary and specialized healthcare services. Study design This was a two-part (formative phase followed ...
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#1Neha Sharma (Amity University)H-Index: 5
#2Devinder Toor (Amity University)H-Index: 5
Purpose of Review Rheumatic heart disease (RHD) is a global health concern especially in low-income settings. Morbidity and mortality data from the World Health Organization (WHO) and global burden studies emphasizes on the prioritization of RHD on a global platform. Genetic, environmental, and socio-economic factors determine the sustainability and progression of RHD in various populations. In developing countries, low socioeconomic status (SES) is a vast and inevitable challenge in combating R...
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#1Marian AbouzeidH-Index: 1
#2Rosemary WyberH-Index: 8
Last. Jonathan R. Carapetis (PMH: Princess Margaret Hospital for Children)H-Index: 63
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ABSTRACTRheumatic heart disease (RHD) is an avoidable disease of poverty that persists predominantly in low resource settings and among Indigenous and other high-risk populations in some high-income nations. Following a period of relative global policy inertia on RHD, recent years have seen a resurgence of research, policy and civil society activity to tackle RHD; this has culminated in growing momentum at the highest levels of global health diplomacy to definitively address this disease of disa...
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