Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum

The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. Most are integral membrane proteins that transport a broad spectrum of substrates across lipid membranes. In insects, ABC transporters are of special interest because of their role in insecticide resistance.We have identified 73 ABC transporter genes in the genome of T. castaneum, which group...