Hyperelongated biglycan: the surreptitious initiator of atherosclerosis.
Abstract
Purpose of review To outline a role for the dermatan sulfate proteoglycan biglycan and specifically its growth factor modified form having elongated glycosaminoglycan chains as being a primary initiator of atherosclerosis. Recent findings Antiatherosclerotic therapies have mostly targeted epidemiologically identified, experimentally confirmed risk factors. The efficacy of such therapies is less than optimal, and rates of cardiovascular disease...
Paper Details
Title
Hyperelongated biglycan: the surreptitious initiator of atherosclerosis.
Published Date
Oct 1, 2008
Volume
19
Issue
5
Pages
448 - 454
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Notes
History