IL-37 protects against obesity-induced inflammation and insulin resistance

Volume: 5, Issue: 1, Pages: 4711
Published: Sep 3, 2014
Abstract
Cytokines of the IL-1 family are important modulators of obesity-induced inflammation and the development of systemic insulin resistance. Here we show that IL-1 family member IL-37, recently characterized as an anti-inflammatory cytokine, ameliorates obesity-induced inflammation and insulin resistance. Mice transgenic for human IL-37 (IL-37tg) exhibit reduced numbers of adipose tissue macrophages, increased circulating levels of adiponectin and...
Paper Details
Title
IL-37 protects against obesity-induced inflammation and insulin resistance
Published Date
Sep 3, 2014
Volume
5
Issue
1
Pages
4711
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.