TRIM22 Inhibits Influenza A Virus Infection by Targeting the Viral Nucleoprotein for Degradation

Volume: 87, Issue: 8, Pages: 4523 - 4533
Published: Apr 15, 2013
Abstract
Tripartite motif (TRIM) protein superfamily members are emerging as important effectors of the innate immune response against viral infections. In particular, TRIM22 was reported to exert antiviral activity against RNA viruses, such as hepatitis B virus (HBV), encephalomyocarditis virus (ECMV), and human immunodeficiency virus type 1 (HIV-1). We demonstrate here, for the first time, that TRIM22 is upregulated by influenza A virus (IAV) infection...
Paper Details
Title
TRIM22 Inhibits Influenza A Virus Infection by Targeting the Viral Nucleoprotein for Degradation
Published Date
Apr 15, 2013
Volume
87
Issue
8
Pages
4523 - 4533
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