Dapoxetine for treatment of premature ejaculation – Authors' reply

With regard to Raimo Salokangas's question about the long-term effects of dapoxetine, adverse events seen in a 9-month open-label extension study (unpublished) were consistent with those seen in the published 3-month phase III studies. In particular, reports of depression, euphoria, and psychosis while on dapoxetine 60 mg occurred in nine (0·5%), three (0·2%), and one (0·1%) of the 1774 patients enrolled in the open-label phase, respectively;...