Effects of Antiviral Therapy for Patients With Inflammatory Bowel Disease and a Positive Intestinal Biopsy for Cytomegalovirus

Background & AimsCytomegalovirus (CMV) is an opportunistic pathogen; documented tissue involvement of patients with inflammatory bowel disease (IBD) is associated with adverse outcomes. We quantified the density of CMV inclusions in biopsy specimens from patients with IBD and assessed their response to antiviral therapy.MethodsIn a case-control study, we identified all small bowel and colon biopsy specimens collected from 1111 patients with IBD...