IFPA Senior Award Lecture: Making sense of pre-eclampsia – Two placental causes of preeclampsia?
Abstract
Incomplete spiral artery remodelling is the first of two stages of pre-eclampsia, typically of early onset. The second stage comprises dysregulated uteroplacental perfusion and placental oxidative stress. Oxidatively stressed syncytiotrophoblast (STB) over-secretes proteins that perturb maternal angiogenic balance and are considered to be pre-eclampsia biomarkers. We propose that, in addition and more fundamentally, these STB-derived proteins...
Paper Details
Title
IFPA Senior Award Lecture: Making sense of pre-eclampsia – Two placental causes of preeclampsia?
Published Date
Feb 1, 2014
Journal
Volume
35
Pages
S20 - S25
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Notes
History