A mitochondrial basis for Huntington’s disease: therapeutic prospects

Volume: 389, Issue: 1-2, Pages: 277 - 291
Published: Dec 29, 2013
Abstract
Huntington’s disease (HD) is an autosomal dominant disease, with overt movement dysfunctions. Despite focused research on the basis of neurodegeneration in HD for last few decades, the mechanism for the site-specific lesion of neurons in the brain is not clear. All the explanations that partially clarify the phenomenon of neurodegeneration leads to one organelle, mitochondrion, which is severely affected in HD at the level of electron transport...
Paper Details
Title
A mitochondrial basis for Huntington’s disease: therapeutic prospects
Published Date
Dec 29, 2013
Volume
389
Issue
1-2
Pages
277 - 291
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