A comprehensive study in triblock copolymer membrane interaction
Abstract
Poloxamers are triblock copolymers made of poly(ethylene glycol)-(poly(propylene glycol))-poly(ethylene glycol). They have been shown to enhance gene transfer in the muscle, and co-administration of polymers and DNA appeared to be crucial to obtain this effect. It is questionable then if some interaction occurs between polymers and DNA. Polymer interaction with membranes represents a second crucial point due to the central hydrophobic part of...
Paper Details
Title
A comprehensive study in triblock copolymer membrane interaction
Published Date
Apr 1, 2011
Volume
151
Issue
1
Pages
57 - 64
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