Genome annotation past, present, and future: How to define an ORF at each locus
Abstract
Driven by competition, automation, and technology, the genomics community has far exceeded its ambition to sequence the human genome by 2005. By analyzing mammalian genomes, we have shed light on the history of our DNA sequence, determined that alternatively spliced RNAs and retroposed pseudogenes are incredibly abundant, and glimpsed the apparently huge number of non-coding RNAs that play significant roles in gene regulation. Ultimately, genome...
Paper Details
Title
Genome annotation past, present, and future: How to define an ORF at each locus
Published Date
Dec 1, 2005
Journal
Volume
15
Issue
12
Pages
1777 - 1786
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Notes
History